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I.グロビン蛋白分解物の血糖値および血清インスリン濃度に及ぼす影響
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JPY
Abstract
Globin digest(GD)is a commercially available oligopeptide mixture derived from edibleglobin proteins developed to effectively lower serum triglyceride levels and to regulate dietaryfat metabolism. In this study, the effect of GD on blood glucose and serum insulin inmice was examined. GD suppressed the elevation of blood glucose in oral glucose tolerancetest. Furthermore, in alloxan−induced diabetic mice for 30 days oral administration of GD, itdecreased blood glucose levels in oral glucose tolerance test. In streptozotocin−induced diabeticmice GD did not exhibit a significant effect.(Jpn Pharmacol Ther 2008;36:1039−44)KEY WORDS Globin digest, Streptozotocin, Alloxan, Diabetes, Glucose, Insulin
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