薬理と治療

Abstract

Objective “KURO－Oolong tea OTPP”is a FOSHU（Food for specified health uses）tea,which inhibits fat absorption, and suppress postprandial triglyceride level. To elucidate potentialof“KURO－Oolong tea OTPP”to reduce risk for metabolic syndrome, we investigatedeffects of the long－term intake of“KURO－Oolong tea OTPP”on body fat mass.Methods We performed a randomized double－blind, placebo－contorolled trial. The subjects（166 men and 134 women）aged from 20 to 65 years old with 25.0≦body mass index（BMI）＜30.0 kg／m2 were randomly divided into two groups；“KURO－Oolong tea OTPP”（OTPP 70mg／350 mL）group, and placebo group. Each subject consumed one bottle with a meal twice aday for 16 weeks.Results Both total fat area（TFA）and visceral fat area（VFA）were significantly reduced in“KURO－Oolong tea OTPP”group compared with placebo group. In addition, body weight,body mass index, body fat ratio, waist size, hip size and skinfold thickness were significantlyreduced in“KURO－Oolong tea OTPP”group. No adverse effects were obserbed in bothgroups.Conclusions The results of this study indicated that the intake of“KURO－Oolong teaOTPP”with a meal could be effective for prevention or amelioration of metabolic syndrome.