薬理と治療

Abstract

Objective Among males with declined sexual function, a different treatment than that against erectile dysfunction may be needed. Korean mountain ginseng（Panax ginseng CA Meyer）are traditional herbal plants to improve sexual functions. In the present study, we investigated the effect of short-term tissue-cultured mountain ginseng（TCMG）intake in improving male sexual function. Methods In a double-blind, placebo-controlled, crossover trial, 26 healthy men（range: 20-49 years old）were randomized to oral TCMG or placebo administration for 7 days. The primary outcomes were International Index of Erectile Function（IIEF）and Aging Male Symptoms （AMS）scores. Results All subjects completed the study. Total score and scores for four out of the five domains of the IIEF after administration were significantly higher than placebo group in the group treated with TCMG（P＜0.05）. Scores at one week post administration period remained significantly higher for the TCMG group（P＜0.05）. Conclusion TCMG administration for 7 days is beneficial in improving sexual function. It was confirmed that its effect also continues 1 week later of administration.