薬理と治療

Abstract

Objectives A randomized, double-blind, placebo-controlled, cross-over study was conducted to evaluate the effects of powdered black tea containing polydextrose on postprandial serum triglyceride. Methods The subjects were 90 healthy volunteers whose fasting serum triglyceride levels were from 120 to 199 mg╱dL. The subjects were randomly divided into two groups and ingested a fat-rich diet and either a test drink containing 5 g（as dietary fiber）of polydextrose or a placebo drink without polydextrose. Serum triglyceride levels were measured before and at2, 3, 4, and 6 hours after ingestion. Results The test drink significantly decreased postprandial serum triglyceride levels at 4 hours and area under the curve after the fat︱rich diet was ingested, compared to placebo drink （P＜0.05）. During this study period, no abnormal changes attributed to test drink were observed. Conclusions These results indicate that powdered black tea containing polydextrose taken with a diet has an inhibitory effect on the postprandial serum triglyceride elevation.