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薬理と治療
Abstract
For players to exert their maximum athletic performance, it is crucial for them to recover promptly from exhausted status caused by exercise, and to regain appropriate physical condition. It has been reported that BCAA(branched-chain amino acids)and citric acid have fatigue-reducing effect for athletes. Based on this report, this research was conducted to explore the possibility of the synergistic fatigue-reducing effect of citric acid and BCAA on exhausted athletes. Forty-four American football players were divided into three groups, and each group was administered BCAA, both citric acid and BCAA, and placebo, in double-blinded manner. The interventional examination was conducted from May 15, 2012 to May 17, and the each group member was applied 120%- strength exercise, compared with the normal training, for 3 and 5 hours╱day. Blood sample were collected from the players 3 weeks prior to, and a day after the examination, and the serum level of CPK activity was compared. Muscle fatigue Test(VAS) and mental fatigue Test (CR-10)Tests were also conducted during the examination to estimate the subjective fatigue level of the players. The blood CPK level which is indicator of muscle injury, increased in all players after the exercise. In addition, the CPK level in citric acid+BCAA group, showed significant lower than that in placebo group(P<0.05). In the CR-10 Test, the mental fatigue level of subject was shown to be lower in citric acid+BCAA group compared with placebo group. These data indicate that simultaneous intake of citric acid and BCAA contribute to the reduction of fatigue caused by exercise.
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