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γ—アミノ酪酸(GABA)の健常人に対する過剰摂取時の安全性の検討―ランダム化プラセボ対照二重盲検並行群間比較試験―
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JPY
Abstract
Objective We conducted a randomized placebo-controlled, double-blind study to evaluate the safety of excessive intake of γ-aminobutyric acid(GABA)in healthy subjects. Methods 30 subjects(18 males and 12 females)were randomly divided into two groups. Each group ingested the test capsule containing 1 g of GABA or the placebo capsule containing 1 g of dextrin for 4 consecutive weeks. Results There were no adverse effects in the blood examinations and physical examinations. Conclusion These results suggested the safety of excessive intake of GABA when taken daily for 4 consecutive weeks by healthy subjects.
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