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Improvement on Bowel Movement by Isomaltodextrin in Women ―A Double—blind Crossover Placebo—controlled Study―
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JPY
Abstract
Objectives As there has been no report on the effect of isomaltodextrin(IMD)on bowel movements in humans, we performed a study to examine the effect in adult women who have 2 to 4 defecations per week. Methods A double-blind, placebo-controlled, crossover study was conducted. Nine subjects were assigned to two groups so that each group had the same number of defecations per week. The subjects received 15 g of IMD(test substance)or 15 g of maltodextrin(MD) (control substance)once daily for 4 weeks, each separated by a 4-week washout period. The water content, pH, and short chain fatty acids(SCFAs)in subjectsʼ feces were determined before intake, and at weeks 2 and 4 during the intake. The subjects filled in a questionnaire on defecation and symptoms. Results The number of days of defecations was significantly higher in IMD intake than in MD intake at week 4. A significant improvement by IMD intake was also noted in a Visual Analog Scale questionnaire on defecation. Furthermore, the amount of total SCFAs in feces was increased after the intake of IMD with a significantly higher Δ value(change from the baseline)in IMD intake than in MD intake at week 2. Conclusions Based on the above, the intake of IMD(15 g╱day)is considered to improve bowel movements.
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