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薬理と治療
Abstract
Objectives We developed a fermented tea by mixing of camellia leaves and third crop green tea leaves at the ratio of 1:9. Feeding a freeze-dried fermented tea extract suppressed white adipose tissue weight and serum and hepatic triglyceride concentrations in SD rats. We investigated the effect of long-term feeding the mixed fermented tea on serum triglyceride levels in dialysis patients. Methods All subjects were dialysis patients. In the first experiment, 11 subjects were divided into the two groups, and 8 subjects were fed the fermented tea extracted 0.5% tea leaves with hot water and 3 subjects were fed green tea or brown rice tea for 3 months. In the second experiment, 27 subjects were fed the fermented tea for 1 month. The amount of the fermented tea leaves used in experiment 2 was 1.5 times higher than that of tea leaves used in experiment 1.Results The concentrations of serum triglyceride were lower, but not significant, in the subjects fed the fermented tea than in those fed green tea or brown rice tea during 3 months. Feeding the 1.5 times stronger fermented tea significantly reduced serum triglyceride level at 1 month after the start of feeding fermented tea. Conclusions These results suggest that a fermented tea made by mixing camellia leaves and third crop green tea leaves has the lowering activity of serum triglyceride concentration in dialysis patients.
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