No data available.
Please log in to see this content.
You have no subscription access to this content.
The full text of this article is not currently available.
健常者を対象としたLactococcus lactis subsp. cremorisFC 含有食品摂取による整腸効果の検証―プラセボ対照ランダム化二重盲検クロスオーバー比較試験―
Rent:
Rent this article for
JPY
Abstract
Objectives The aim of this study was to evaluate the effect of Lactococcus lactis subsp. cremoris FC on fecal properties and fecal microflora in healthy subjects prone to constipation. Methods In total, 50 volunteers(seven men and 43 women)were randomized into two groups and given 100 mg of L. lactis subsp. cremoris FC(test)or dextrin(placebo)daily for 2 weeks in a double-blind, placebo-controlled, cross-over study. The fecal microflora was analyzed using the DNA extracted from feces and a real-time polymerase chain reaction. Results Compared with the ingestion of placebo, the defecation frequency significantly increased(days╱week, P<0.05; times╱week, P<0.001)with the ingestion of L. lactis subsp. cremoris FC. The total bacterial count(log)and Lactobacillus sp. bacterial count(log)significantly(P<0.05)increased 2 weeks after the ingestion of test. Conclusion These results suggest that the continuous ingestion of L. lactis subsp. cremoris FC caused changes in intestinal microflora, improving defecation status and fecal characteristics in healthy subjects prone to constipation.
Full text loading...
/content/article/0386-3603/45060/989