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健常者を対象とした脳機能改善に及ぼすプラズマローゲン摂取の影響―無作為化二重盲検プラセボ対照並行群間比較―
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JPY
Abstract
Objectives To examine the effects of plasmalogen on brain function, a randomized double-blind placebo-controlled parallel group comparison study was conducted with 50 to 70 years old healty male and female who were aware of forgetfulness. Methods Plasmalogens used in this study were prepared from chicken breast meat, and were administered of low dose(1 mg plasmalogens╱day)to high dose(100 mg plasmalogens╱day) for 12 weeks to subjects. Results In Urbans neuropsychological test, significant scores were observed at the high dose and low dose groups compared with 12 weeks after intake to before intake in the overall evaluation item, respectively. Even in Cognitrax test, the score in some items increased significantly compared with before to after intake. The safety of plasmalogens was confirmed, because no adverse events were obserbed during this study. Conclutions It can be said that plasmalogens derived from chicken beast meat can be safely consumed in everyday diet and be expected to improve cognitive functions and prevent alzheimer disease.
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