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ピセアタンノール摂取による肌の水分や弾力へ及ぼす効果―ランダム化二重盲検プラセボ対照並行群間比較試験―
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JPY
Abstract
Objectives The aim of this study was to investigate the effect of a dietary supplement containing piceatannol on skin in healthy subjects with dry skin. Methods A randomized, double blind, placebo-controlled parallel-group, comparison study was conducted in 36 healthy subjects(30-60 years old)with dry skin. They were randomly divided into two groups and ingested either the test product(125 mL drink containing 10 mg piceatannol derived from passion fruit seed extract)or the control product(placebo drink)three packs per day for 8 weeks. The outcomes about skin condition were evaluated using moisture content of horny layer, Trans-epidermal Water Loss(TEWL)and viscoelasticity of the face. This study was registered in UMIN-CTR(UMIN000030491). Results The water content and elastic recovery from the pretrial were significantly increased at 8 week in the test product containing piceatannol compared to the placebo group. Conclusions These result suggested that the daily supplementation of piceatannol derived from passion fruit seed extract is effective for skin moisture.
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