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薬理と治療
- Authors: Ryuichiro Suzuki1, et al.
Abstract
Objective The aim of this systematic review was to synthesize data from randomized controlled trials(RCTs)investigating the effects of oolong tea on postprandial triglyceride(TG) levels. Methods A literature search was performed using the electronic databases of PubMed, Cochrane Library, EMBASE, Ichushi-Web(Japan), JDreamIII(Japan), and Thai-Journal Citation Index(TCI)search (Thailand). We detected 233 related literature articles in the databases. Of these, two studies fulfilled the eligibility criteria of our study. Results A total of 50 participants from the two studies fulfilled the selection criteria, and the interventions of both studies were oolong tea rich in oolong tea polymerized polyphenols (OTPP). OTPP dosage ranged from approximately 70 mg and resulted in a significantly more pronounced decrease in postprandial TG levels at the 4th hour after a high-fat meal intervention(mean difference(MD): -18.87 mg╱dL, (95% confidence interval(CI)-22.92 to-14.82), P<0.00001, I2=0%, n =2 trials)and also at the 5th hour after a high-fat intervention(MD: -12.24 mg╱dL, (95% CI-16.47 to-8.01), P<0.00001, I2=0%, n=2 trials) as compared with controls, respectively. Conclusion The current systematic review provides some evidence that oolong tea, especially OTTP-enriched oolong tea, may have a beneficial effect on postprandial serum TG levels. However, the data are limited and the included trials had methodological limitations. Results from large, rigorously designed RCTs are needed to assess the effect of oolong tea consumption on postprandial serum TG levels.
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