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アロマ含有キャンディの摂取による風邪症状の緩和効果について―ランダム化プラセボ対照並行群間比較試験―
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JPY
Abstract
Objective The aim of the present study was to evaluate the effect of aromatic compound and polyphenol-containing candy(hereafter referred as“aroma candy”)on the general observation of cold symptoms. Methods The effects of aroma candy on the specified cold symptoms was evaluated in a randomized, placebo-controlled parallel-group comparison study with fifty-one(51)healthy volunteers. Test article and placebo groups were treated with three(3)drops╱day for twenty-eight(28)consecutive days in which Visual Analogue Scale(VAS)method was used to evaluate the effect of aroma candy on symptomatic aspects accompanied with cold. Results In the VAS evaluation of both groups before the treatment, the test article group showed marginally higher incidence than the placebo group in a discomfort of the throat. In a comparative assessment of cold symptoms between before and after treatment, it was shown that the subjective scoring of a hoarse voice after treatment with the test article was significantly lower than that before treatment. It was also demonstrated that a throat discomfort and sore throat score after treatment with the test article was marginally lower than that before treatment, however the placebo group did not show any significant difference, even though in a marginal manner, in the comparative before-after evaluation. Conclusions The above-mentioned observation suggests that the aroma candy taken as a daily diet is beneficial candidate to relieve symptoms resulting from a cold.
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