No data available.
Please log in to see this content.
You have no subscription access to this content.
The full text of this article is not currently available.
Safety Evaluation of Collagen Peptide Ingestion―Randomized, Placebo—controlled, Double—blind, Parallel—group Trial―
Rent:
Rent this article for
JPY
Abstract
Objective This study was to evaluate the safety of oral intake of fish-derived collagen peptide(FCP)in healthy Japanese adult subjects. Methods A randomized, placebo-controlled, double-blind, parallel-group trial was conducted in 50 healthy volunteers aged 30-59 years who were experiencing daily tiredness and fatigue. Subjects were equally, but randomly, assigned to fish-derived collagen peptide group (FCP group, n=25)and placebo group(P group, n=25) using a computerized random-number generator and ingested 5 g of either FCP as the active food or dextrin as the placebo food, twice per day(after breakfast and dinner)for 8 weeks. Physical examination, blood analysis, urinalysis, and subjective symptoms were examined at baseline and after 8-week ingestion of the test food. Results The analysis set was intention-to-treat including 25 participants(45.9±6.9 years) in the P group and 25 participants(46.3±6.4 years)in the FCP group. No clinically concern was observed in physical examination, blood analysis, urinalysis, and subjective symptoms. Furthermore, no adverse effect attributable to test foods intake was observed. Conclusions The results indicated that continuous oral intake of FCP is safe in healthy Japanese adults under the conditions of this study. Foundation Nippi. Inc.
Full text loading...
/content/article/0386-3603/46110/1859