薬理と治療

Abstract

Background Pharmaceutical intervention（prescription modification via prescription inquiries） by hospital pharmacists has been reported to improve the safety of pharmacotherapy. However, the reporting on pharmaceutical intervention by community pharmacists has been insufficient. Methods In this study, we analyzed cases of pharmaceutical intervention by community pharmacists（PREAVOID reports）collected by the Kurume Mii Pharmaceutical Association. Results In 67％ of the cases, the patients were≥60 years of age. The number of cases in which adverse drug reactions（ADRs）or the aggravation of ADRs was avoided was 287 and 10 respectively. Checking the medication notebook and the patientʼs medication history was helpful in 61％ of the cases in which ADRs were prevented. Consequently, patients could avoid contraindications from co-administration and duplicated administrations. Patients recovered from adverse events in pharmaceutical interventions in which patient symptoms and blood test results were studied. The estimated pay out for reactive relief systems for ADRs is approximately 1000 times higher than the additional dispensing fees associated with pharmaceutical interventions. Conclusions Risk evasion through these interventions by community pharmacists suppressed the development of side effects, avoided the recurrence of ADRs, and reducing exacerbation or worsening of primary disease. The economic impact was also high.