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Inhibitory Effect of Epigallocatechin Gallate—containing Foods on Plaque Formation and Adhesion―A Randomized Placebo—controlled Double—blind Crossover Study―
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JPY
Abstract
Objectives The aim of this study was to evaluate the effect of the ingested foods containing the green-tea polyphenol epigallocatechin gallate(EGCg)on dental plaque formation and adhesion. Methods A randomized placebo-controlled double-blind crossover study was carried out on 23 healthy, female university students(aged 20︱23 years, effectiveness analysis subject number: 20). The study participants were forbidden from using toothbrushes, and at every meal they were instructed to ingest food containing 6 mg of EGCg. Results The status of plaque adhesion(plaque index)showed a significant improvement (P<0.05)after three days. Conclusions In conclusion, EGCg-containing foods have an inhibitory effect on dental plaque formation and adhesion, and are suitable for individuals who are concerned about oral hygiene. This trial was registered at http://www.umin.ac.jp/ctr/ as UMIN000029694.
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