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健康成人を対象にした新規チョコレート摂取時の血糖値推移に関する検討―プラセボ対照3—way オープンクロスオーバー比較試験―
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JPY
Abstract
Objectives The aim of the present study was to investigate an effect of chocolate containing fructooligosaccharides on postprandial blood glucose in healthy human. Method Three randomized and crossover trials were conducted. Eleven subjects ingested a chocolate with(test diet)or without(control diet) fructooligosaccharides, and sucrose only. Blood glucose was measured before and 15, 30, 45, 60, 90, and 120 minutes after ingestion. Results Analysis of all subjects revealed no significant difference between the control and test diets. However, the test diet showed significant decrease in incremental area under the curve(ΔAUC)when compared with sucrose only while control diet did not change. Compared to sucrose only, the chocolate with or without fructooligosaccharides significantly decreased blood glucose and Cmax. Conclusions These results indicated that ingesting chocolate with or without fructooligosaccharides would elicit a significant lower blood glucose than sucrose alone. It seems likely that the chocolate with fructooligosaccharides may exhibit its hypoglycemic effects by decreasing the ΔAUC. (UMIN ID:UMIN000034606)
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