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酢酸菌(Gluconacetobacter hansenii GK—1)は健常者の鼻の不快感を軽減する―無作為化二重盲検プラセボ対照並行群間比較試験―
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JPY
Abstract
Objectives We aimed to determine whether the ingestion of acetic acid bacteria could reduce nasal discomfort. Methods We conducted a randomized double-blind placebo-controlled study. Eighty Japanese males and females(mean age:38.6 ±1.2 years)with complaints of daily nasal discomfort were randomly assigned to an acetic acid bacteria group or a control group. The subjects ingested acetic acid bacteria(4⊠1010 cells╱day)or placebo for 8 weeks. Nasal discomfort was evaluated using the Japanese Rhinoconjunctivitis Quality of Life Questionnaire at preingestion and at 4 and 8 weeks during the ingestion period. Results The acetic acid bacteria group had a significantly lower nasal discomfort score compared to the control group at 4 weeks after ingestion(P<0.05)with no adverse effects observed. Conclusion Our findings suggest that the continuous ingestion of acetic acid bacteria relieves nasal discomfort(. UMIN000033383)
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