Full text loading...
薬理と治療
Abstract
Objective The aim of the present study was to examine whether the intake of a single drink containing psicose(allulose)affects fat oxidation in healthy adults during exercise. Methods A randomized, double-blind, placebo-controlled, cross-over trial was conducted for 48 healthy male subjects aged from 20 to less than 40 years old. After overnight fasting, the subjects ingested a water drink containing 5 g of psicose or an identical tasting placebo drink not containing psicose 30 min before exercising. An ergometer was used for 60 min of exercise and the exercise intensity was set to moderate based on the 60% ventilation threshold(60% VT)for each subject. Indirect calorimetry was performed during exercise to measure the VO2 and VCO2 to calculate fat oxidation, carbohydrate oxidation, and energy expenditure. Results The psicose drink significantly increased the incremental area under the curve(ΔAUC)for fat oxidation and decreased the ΔAUC for carbohydrate oxidation during exercise from 10 to 60 min compared with the placebo. There was no significant difference in energy expenditure, and no adverse effects were observed with either drink. Conclusions The intake of a single psicose-containing drink increased fat oxidation during moderate exercise, suggesting that fat was preferentially utilized as an energy substrate instead of carbohydrates. Thus, psicose may enhance fat oxidation during exercise, and may be added to foods to prevent the development of obesity and to maintain general health. (UMIN︱CTR ID: UMIN000033260)
Data & Media loading...