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健康成人男性を対象としたフラクトオリゴ糖含有チョコレート摂取時の血糖値推移に関する検討―プラセボ対照オープンクロスオーバー比較試験―
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JPY
Abstract
Objectives The aim of the present study was to investigate the effect of chocolate containing fructooligosaccharides on postprandial blood glucose in healthy males. Methods This was a randomized, open-label, placebo-controlled, crossover study. Ten male subjects(aged 51.3±4.4 years)ingested chocolate with(test diet)or without(control diet) fructooligosaccharides. Blood glucose and plasma insulin levels were measured before and 15, 30, 45, 60, 90, and 120 minutes after ingestion. Results Blood glucose at 30 minutes after ingestion of the test diet was significantly lower than after ingestion of the control diet. Plasma insulin levels at 30 and 60 minutes after ingestion of the test diet were also significantly lower than after ingestion of the control diet. Moreover, the change in area under the curve(ΔAUC)of plasma insulin levels following ingestion of the test diet was significantly lower than that following ingestion of the control diet. Conclusions The results of this study suggest that ingestion of chocolate containing fructooligosaccharides elicits significantly lower blood glucose and plasma insulin levels than ingestion of chocolate that does not contain fructooligosaccharides.
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