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ココア摂取による認知機能へ及ぼす効果―ランダム化プラセボ対照二重盲検クロスオーバー比較試験―
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JPY
Abstract
Objective The aim of this study was to investigate the effect of oral intake of cocoa on cognitive function on healthy subjects. Methods A randomized, placebo-controlled, double-blind cross-over, comparison study was conducted in 15 healthy subjects(20-39 years old). The subjects were given either the test product(20 g cocoa powder containing 30 mg cacao flavanols in 120 mL hot water)or the control product(placebo powder in hot water)30 min before the Japanese version of the CNS Vital Signs(Cognitrax). Results The cognitrax individual scores of visual memory test(immediate)and response time in 4-part continuous performance test were significantly improved in the test cocoa group compared to the placebo group. Conclusions The results suggested that oral intake of cocoa may be effective for cognitive function(. UMIN-CTR000036896)
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