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Safety Evaluation of Excessive Intake of Chicken Leg Extract(HAS—Ⅱ®) in Healthy Adult Subjects―A Randomized, Placebo—controlled, Double—blind Study―
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JPY
Abstract
Objective The objective of this study was to evaluate the safety of excessive intake of chicken leg extract(CLE)in healthy Japanese adult. Methods A randomized, placebo-controlled, double-blind study was conducted in 34 subjects(19 men and 15 women). During 4 consecutive weeks, subjects ingested 1 g/day of CLE or placebo. Physical parameters, blood parameters, urine parameters and subjective symptoms were measured throughout the study. Results No adverse effects and no clinically concerning changes in physical, blood and urine parameters were observed. Conclusion It was suggested that the excessive intake of CLE(1 g/day)was safe in healthy adults.
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