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Effect of Intervention by Hospital Pharmacists on the Number of Drugs for At—home Patients―A Retrospective Observational Study―
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JPY
Abstract
Background Pharmacotherapy is performed in accordance with the guidelines for each disease. The number of drugs to be taken increases when a patient has multiple diseases. Polypharmacy may be a problem owing to increased side effects and interactions. Methods The subjects were at/home patients(patients who received home visits)during the year from April 2016 to March 2017. Age, sex, disease, number of drugs, and reason for drug changes were compared in patients who were hospitalized and patients who were not hospitalized within 1 year of intervention. Results Many at-home patients had multiple disease(75.61%). The number of drugs was reduced after 12 months compared with the time of intervention(P<0.01). Among prescription changes, pharmacists proposed most of the prescription changes(91.34%). In addition, the number of drugs taken by at-home patients who were not hospitalized within 1 year of intervention was reduced (P=0.037). However, this reduction was not seen at-home patients who were hospitalized within 1 year of intervention. Conclusions If pharmacists can actively intervene and reduce polypharmacy in at-home patients, this may reduce unnecessary hospitalization due to polypharmacy interactions and side effects. It is possible that this intervention may lead to an overall reduction in the number of inpatients.
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