No data available.
Please log in to see this content.
You have no subscription access to this content.
The full text of this article is not currently available.
高脂肪飼料摂取モデルマウスの血中脂質および肝細胞中脂肪小滴に与える防風通聖散・大柴胡湯の影響
Rent:
Rent this article for
JPY
Abstract
We have investigated the effects of hypolipidemic agents on obesity, dyslipidemia and fatty liver in mice fed a high-fat diet. Intakes of fibrous supplement and hypolipidemic drugs, eicosapentaenoic acid, fluvastatin, probucol and colestimide decreased plasma lipids and fatty drops in liver of mice fed a high︱fat diet. Japanese herbal medicines, Bofutsushosan and Daisaikoto have been used as an anti/obesity agent, a hypocholesterolemic agent and a therapeutic and/or preventive agent for cholesterol gallstone disease with hypertriglyceridemia. Hence, we investigated the effects of two medicines on plasma lipids and hepatic fatty drops in mice fed a high-fat diet. These medicines lowered the body growth, the plasma levels of lipids and the numbers of hepatic fatty drops in mice. Besides, Daisaikoto seemed to be more effective than Bofutsushosan in the body growth. Improvement of lifestyle and timely using of Kampo-remedies might be beneficial for prevention of obesity, dyslipidemia and fatty liver.
Full text loading...
/content/article/0386-3603/48020/175