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デビルズクローエキス含有食品の継続摂取による膝関節の違和感に対する影響―ランダム化二重盲検プラセボ対照並行群間比較試験―
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JPY
Abstract
Objective We investigated oral intake of Harpagophytum procumbens extract (Harpagoside 13%). In this study, A randomized double-blind placebo-controlled study was conducted, to assure the effect on discomfort in knee joints. Method 41 Japanese healthy men and women(range 40-74 years old)took either 27 mg/day Harpagoside or placebo, then we measured the subjective scores in accordance with JKOM questionnaires after 8 weeks administration. Results VAS score quantifying discomfort in knee was significantly improved(P<0.05)in Harpagoside group at 8 weeks, and the further statistical analysis verified the correlation between the subjective improvement in knee and effect to reduce physical stress in knee.Conclusion Oral intake of 27 mg Harpagoside via high purified Harpagophytum procumbens extract reduced the discomfort when to bend or stretch knee. (UMIN-CTR ID: UMIN000037556)
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