Full text loading...
薬理と治療
Abstract
Objective Improving the quality of sleep is important to reduce fatigue and stress, to maintain well physical and mental condition, and to achieve high performance. Previous study suggested that amino acids-containing food is indicated to improve the quality of sleep and to reduce fatigue by long-term ingestion. Also, L-theanine is reported that it boosts the quality of sleep, and it could be considered that a synergistic effect might be obtained by amino acids-containing food with L-theanine. So the aim of this study was to evaluate the possibility to enhance the effects improving the quality of sleep by their combination. Methods Three types of food capsulated samples were prepared to be containing respectively: sample A; amino acids(arginine, lysine and ornithine at low doses), sample B; sample A with L-theanine, and sample P as placebo. Each sample was ingested for 7 consecutive days. Factors of the quality of sleep were evaluated by OSA sleep inventory MA version and so on. Results By OSA questionnaire, among all groups, no remarkable difference was observed at before or after of ingestion. In each group taking sample A or B, the factors asʻsleepiness at waking upʼandʻrecovery from fatigueʼis significantly improved, and more, in group B, the factors asʻfalling asleep and sleep continuityʼʻ, sleeping periodʼ, and total of factors. Conclusions It is suggested that the combination of amino acid-containing food with L-theanine, both have sleep-improving effects, could enhance the effects improving the quality of sleep.(UMIN000034664)
Data & Media loading...