Therapeutic Research

Abstract

Background and Objective：Hypertension treatment is mainly conducted with the medical intervention based on the evidence. In the real world, however, inadequate achievements in reaching the designated antihypertensive goal have been experienced sometimes despite following the guidelines. The purpose of this study is to examine my trial for achieving the goal by the antihypertensive therapy. Results：The samples are of the 1752 patients（male 914, female 838, average age 64.6）who have been under treatment in my clinic. They were able to lower blood pressure with twenty‒four‒hour continuous effect by dividing the same amount of antihypertensive drug which is supposed to be taken once a day to twice a day, both in the morning and in the evening. This method of taking drugs has more sustainable effect compared to the once‒a‒day intake. Furthermore it made the patients aware of the disease and be adherent in taking the drug. In the end this evidence proves that there are more advantages dosing the same amount of the drug twice a day. The algorithm of the main drugs for lowering blood pressure for hypertension used in my clinic has also been verified,such as menopausal hypertension, early morning hypertension and resistant hypertension. As a result of examination at my clinic, combined use of beta blockers and alpha blockers was necessary and useful for treatment of these cases.