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薬理と治療
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プロバイオティクス Lactobacillus gasseri SBT2055 を含有する発酵乳の摂取による肥満者の内臓脂肪低減効果の検証
JPY
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ライフサイエンス出版
Abstract
Objective Lactobacillus gasseri(L. gasseri)SBT2055 inhibits dietary fat absorption in rats, and exerts preventive effects on abdominal adiposity in both rats and humans. We evaluated the effects of the L. gasseri SBT2055 on body fat accumulation in obese subjects. Methods Volunteers(n=101;54 male, 47 female;BMI of 25 to 30 kg/m2)were given 100 g of fermented milk containing L. gasseri SBT2055(107 cfu/g)or placebo daily for 12 weeks. Results After 12 weeks, abdominal visceral fat area in the test sample group was significantly reduced compared with the placebo group. Conclusions These results indicated that SBT2055-fermented milk reduces the abdominal adiposity including visceral fat.
