薬理と治療

Abstract

Objectives To evaluate effects of a food containing Eucommia leaf extract on reducing body fat reduction for 12 weeks after ingestion. Methods This study was a randomized, double-blind, placebo-controlled, parallel-group study. Healthy males and females with obese tendencies（BMI: 25-30）were divided into the test food group and the placebo group and given the test products containing Eucommia leaf extract（6 tablets per a day; 12 weeks）or the control products not containing Eucommia leaf extract（6 tablets per a day; 12 weeks）, respectively. Weight, body fat percentage, BMI, blood pressure, pulsation, hematologic and blood biochemical screening tests were examined at Week 8 and Week 12, after ingestion, respectively. CT scanning test analyzed with FatScan（visceral fat）was conducted at Week 12. Results By CT scanning test analyzed with FatScan, it was demonstrated that visceral fat was significantly decreased in the test food group compared with that of the placebo group at Week 12. Body fat percentage also was significantly decreased in the test food group compared with that of the placebo group at Week 12. Conclusion It was shown that a food containing Eucommia leaf extract was effective for body fat reducing.