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薬理と治療
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健康な成人におけるぶどう糖ラムネ菓子摂取によるワーキングメモリーと注意力の改善―ランダム化二重盲検プラセボ対照クロスオーバー比較試験―
JPY
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ライフサイエンス出版
Abstract
Objective The aim of this study was to investigate the effect of oral ingestion of fizzy candy （Ramune candy）on cognitive function on healthy subjects. Methods A randomized, double-blind, placebo-controlled cross-over, comparison study was conducted in 14 healthy subjects（Mean±SD 33.9±1.3, Median 35.5 years old）. The subjects were given either the test product（29 g Ramune candy containing 26 g hydrous crystal glucose, Morinaga & Co., Ltd., Tokyo）or the control product （placebo candy not containing glucose）30 min before the Japanese version of the CNS Vital Signs（Cognitrax）. Results The cognitrax individual tests scores of 4-part continuous performance test related to working memory and sustained attention were significantly improved in the Ramune group compared to the placebo group. Conclusions The results suggested that oral ingestion of 26 g hydrous crystal glucose may be effective for cognitive function. （UMIN-CTR000036893）
