薬理と治療

Abstract

Objectives　The aim of this study is to elucidate the effects of banana intake on healthy subjects on their intestinal flora composition and on blood biochemical markers. Methods　A randomized parallel-group comparison study was conducted on 28 healthy adults. Participants were randomized into two groups; one group to take 120 g of banana every day; another group with no test food added to their everyday food, for four weeks. Fecal sample, serum biomarkers, body composition were evaluated for intestinal flora composition and blood chemistry variation before and after the intervention term. Results　The blood biochemistry showed statistical increase of magnesium in the banana group. Vitamin B6 showed no statistically significant difference between the two group after four weeks. In intestinal flora test, Akkermansia decreased significantly in banana group. Bilophila decreased significantly in banana group. Megamonas significantly decreased in both banana group and control group. Megasphaera significantly decreased in banana group. Phascolarctobacterium decreased significantly in control group. Roseburia increased significantly in control group. Ruminococcus significantly decreased in banana group. Conclusions　The results suggest that taking banana may contribute to increasing magnesium which is a mineral that Japanese peopleʼs intake is lower than recommended volume. Some unfavorable flora may decrease by taking banana. UMIN ID：UMIN000040523