薬理と治療

Abstract

Background　There have been almost no systematic reports that examined unmet medical needs based on the content of inquiries to the clinical studies consultation service. Method　From April 2018 to November 2020, among the inquiries received at the clinical studies consultation service of the Kyoto University Hospital, the number of clinical trial survey requests was totaled and the disease areas with high patient needs were examined. Results　During the study period, there were 123 survey requests regarding clinical trials that could be participated. Of these, the largest number of consultations was regarding cancer（60 cases, 49％）. Other than that, there were 15 consultations（12％）regarding nervous system diseases. Among the consultations on cancer, the most common was diseases of the digestive system（25 cases, 42％）. Among the consultation cases for which information on clinical trials that could be participated was not found, nervous system diseases were the most common. Discussion　The high proportion of cancer and nervous system diseases in the disease areas requested to be investigated in clinical trials was similar to the results of investigations by other methods in the past. Our study reaffirmed the high medical needs in these disease areas. Conclusion　To clarify the effectiveness of examining unmet medical needs from the survey contents of the consultation service should be followed by further examination.（Jpn Pharmacol Ther 2022；50 suppl 1：s21‒26）